- Accountable for the execution of cellular and molecular-based experiments for the identification and evaluation of genomic-based predictive response biomarkers for specific compounds in the Oncology pipeline
- Collaborate with cross-functional groups including internal Oncology Research and Bioinformatics personnel Generate technical reports, manuscripts and present data at internal meetings
- Assist with routine laboratory management issues
- Required to design and execute cellular- and molecular-based assays for the identification and validation of predictive response biomarkers
- PCR / RFLP analysis
- Taqman real-time PCR / analysis
- Western blot analysis
- RNA/DNA/miRNA isolation/ analysis
- Cell culture
- Cellular assays when needed
- Analyze public and internal genomic datasets in collaboration with Bioinformatics personnel
- Generate technical reports, manuscripts and present data at internal meetings
- Responsible for the conduct, analysis and reporting of data in accordance with requirements set forth by the department
- Ensure maintenance of detailed documentation of assay development methods and performance; record experimental data and accurate and highly organized laboratory notebooks
- Represent biomarker team at therapeutic working group meetings, as required.
- Assist with routine management of the Biomarker laboratory
- Experienced in designing and executing cellular- and molecular-based assays for the identification and validation of predictive response biomarkers
- PCR / RFLP analysis
- Taqman real-time PCR / analysis
- Western blot analysis
- RNA/DNA/miRNA isolation/ analysis
- Cell culture
- Cellular assays when needed
- Experienced analyzing public and internal genomic datasets in collaboration with Bioinformatics personnel
- Experienced generating technical reports, manuscripts and present data at internal meetings
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